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The primary cause of nigral dopaminergic cell death in PD is oxidative injury and a neurotoxin that causes oxidative stress by binding to the dopamine transporter and delivers its toxicity to DN by generating reactive oxygen species (ROS) such as superoxide radicals [46] and kills them

The application of antibiotics for managing wound infections is constrained by the rising prevalence of multidrug-resistant bacteria 34

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

Biol Psychiatry Cogn Neurosci Neuroimaging 6(6):607615 Lu T et al (2004) Gene regulation and DNA damage in the ageing human brain

People with Digestive Issues : Individuals with Crohns disease, celiac sprue or individuals who have suffered mucosal injury through surgery or gastric banding surgery are unable to absorb vitamin B12