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After treatment, a mean increase of 75.27 mmHg in the PFO was noticed in the HABIT group, which was numerically higher than that of 51.23 mmHg in the control group, but the difference was not statistically significant ( p = 0.113, Fig

In addition, that dihydromyricetin-induced ROS downregulation was demonstrated to activate caspase-9 and trigger PARP cleavage, leading to apoptotic cell death in human hepatoma HepG2 cells [50], and that the flavonoid dihydromyricetin reportedly induced apoptosis in Hepal-6 hepatoma cells by reducing ROS generation via the TGF-/Smad3 pathway [51]

doi: 10.1172/JCI44678

et al., 2021), and cucumber (Wang et al., 2019)