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Moreover, elevated Holdemanella has been associated with reduced right amygdala and hippocampal volumes (Wanapaisan et al., 2022) brain regions consistently reduced in PTSD individuals (Ben-Zion et al., 2023)

Two previous studies [45, 46] found high levels of total B6 in the plasma, and in those papers it was hypothesized that it might be due to an impaired conversion of B6 to the active form, P5P
