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Researchers have also investigated its contribution to experimental studies involving adipocyte biology, metabolic regulation, and intracellular energy pathways

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Tbx1 is only expressed in a subset of brain vessels (1.5% of brain cells) in the adult mouse (24), but it excludes significant noncell-autonomous transcriptional effects on the brain parenchyma

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Clinically, however, the evidence is mixed : Vitamin B12 has a well-established role in energy metabolism, especially in deficient individuals