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[2] When to Seek Further Medical Advice About B12 Patients should maintain regular contact with their GP or healthcare team throughout B12 treatment, but certain situations warrant urgent medical review

Zabetian A, Hadaegh F, Azizi F

Abbreviations FDA: Food and Drug Administration DMBA: 7,12-Dimethylbenz[a]anthracene TPA: 12-O-Tetradecanoylphorbol-13-acetate TNF- : Tumor Necrosis Factor alpha IL-6 : Interleukin-6 IL-1 : Interleukin-1 beta MDA: Malondialdehyde SOD: Superoxide Dismutase GSH: Glutathione VEGF: Vascular Endothelial Growth Factor VEGFA: Vascular Endothelial Growth Factor A PPI : Protein-Protein Interaction GO: Gene Ontology KEGG Kyoto Encyclopedia KEGG: Kyoto Encyclopedia of Genes and Genomes MCL: Markov Cluster Algorithm STRING: Search Tool for the Retrieval of Interacting Genes/Proteins NMSC: Non-Melanoma Skin Cancer BCC: Basal Cell Carcinoma SCC: Squamous Cell Carcinoma ROS: Reactive Oxygen Species PBS: Phosphate-Buffered Saline ELISA: Enzyme-Linked Immunosorbent Assay ANOVA: Analysis of Variance SD: Standard Deviation BAX: Bcl-2 Associated X Protein BCL2: B-Cell Lymphoma 2 CASP3: Caspase-3 SOD1: Superoxide Dismutase 1 GPX1: Glutathione Peroxidase 1 GSR: Glutathione Reductase GSTP1: Glutathione S-Transferase Pi 1 NF-B : Nuclear Factor Kappa-B STAT3: Signal Transducer and Activator of Transcription 3 Wnt: Wingless-related Integration Site signaling pathway -catenin : Beta-catenin DMSO: Dimethyl Sulfoxide 5-FU : 5-Fluorouracil IHC: Immunohistochemistry qPCR: Quantitative Polymerase Chain Reaction ARRIVE: Animal Research: Reporting of In Vivo Experiments AVMA : American Veterinary Medical Association References Wi K, Hwang SY, Kim YG, Lee SI, Lee CJ, Bang G, et al

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