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Studies having higher proportion of male par- ticipants had larger SMDs, suggesting that AD studies with more male participants reported lower GSH com- pared to controls

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Acknowledgements This work was supported in part by the Hospital for the Consumptives of Maryland (Eudowood) and the Life and Breath Foundation

Also, it is necessary to establish a robust framework for future management of OSF, as it is expected to shift towards a more proactive, personalized, and resource-sensitive approach