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Oral therapy is generally unsuitable for pernicious anaemia or conditions affecting the terminal ileum (where B12 is absorbed), as these patients lack intrinsic factor or have damaged absorption sites

In controlled laboratory studies, Epitalon reproduces the mentioned benefits

In particular, during the acute phase, in which HCV replicates at a high rate, a marked oxidative stress due to the NOX4 isoform, ubiquitously expressed in parenchymal and non-parenchymal liver cells, has been observed, as well as a concomitant decrease in GSH