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Gan et al observed thickened myelin sheath and increased cross-sectional area of target muscle cells after daily mecobalamin administration intraperitoneally in rats with sciatic nerve injury 15

doi: 10.3390/ijms22105074 60

Theoretically, the intracellular assimilation of folic acid via dihydrofolate reductase might enhance thymidylate synthetase by bypassing the methylfolate trap, thereby allowing cellular proliferation to progress temporarily

Therefore, there is growing interest in determining which other epigenetic modifications might play a key regulatory role

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