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GHK-Cuis a naturally occurring copper-binding tripeptide found in human plasma, studied for its role in skin regeneration, collagen synthesis, and tissue repair

For instance, the heparin-binding domain of heparin-binding epidermal growth factor (HB-EGF) has been employed to enhance the retention of IGF-1 in cartilage in vivo , resulting in increased therapeutic efficacy in a rat medial meniscal tear model of OA

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