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Description
Low glutathione levels can lead to decreased energy, increased inflammation, and cognitive decline
Changes in GCL activity can result from regulation at multiple levels affecting only GCLC or both GCLC and GCLM subunits
Chronic alcohol use has long been known to increase activation of this system, resulting in elevated levels of angiotensin II in humans
Giloteaux L, O'Neal A, Castro-Marrero J, Levine SM, Hanson MR
2015;6:e1663
