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Its atherogenic effects include abnormalities in cholesterol and bile acid metabolism, which cause inflammation and foam cell production

Novelty and context To the best of our knowledge, this is the first study to employ immunohistochemical CD38 and GLUT1 as hepatic oxidative/metabolic stress readouts specifically in an MTX-induced hepatotoxicity model

However, the relationship between testis functionality and the bacterial composition of the microbiota remains significantly less studied than the gutbrain axis

Robert Koeth Zeneng Wang Bruce Levison Stanley Hazen Intestinal microbiota metabolism of choline and phosphatidylcholine produces trimethylamine (TMA), which is further metabolized to a proatherogenic species, trimethylamine-N-oxide (TMAO)