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Data analysis after study completion showed a trend, and it is displayed in Fig

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Targeting NAM binding site As an endogenous product of the NNMT-catalyzed reaction, 1-MNA (IC 50 = 9.0 0.6 M) is a prototype NNMT inhibitor that engages the NAM binding site, which has been traditionally used in pharmacological evaluations of NNMT functions

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