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This displaced material can compress adjacent nerve roots, triggering pain, numbness, tingling, or weakness in the areas those nerves serve

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Calpain activation might play an important role in pathological cascades such as diffuse axonal injury, as calpain-mediated proteolysis of spectrin has been detected acutely after injury

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This is an example of the inconsistent interpretations of the related substance language included in many WADA categories