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Under conditions of iron overload, the increased expression of HO-1 competes with LDHB for binding to LONP1, forming a stable complex
Diminished PIEZO1 activity decreases stiffness, whereas enhanced PIEZO1 activity increases stiffness of rat tail tendons
Finally, increasing evidence of the therapeutic effect of immune checkpoint inhibitors in ovarian cancer has been reported
Early identification of resistance mechanisms, combined with proactive surveillance, is therefore essential to contain the spread of resistance and sustain the efficacy of current interventions
Spencer and Hu, 2020
