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pentose phosphate pathway and glutathione The in health disease The pentose phosphate pathway (PPP)
Description
Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a Mendelian randomization study

This highlights the interdependence between eNOS-derived NO and DHFR stability

An epidemiological meta-analysis reported that lipid-lowering statins are protective against PD symptoms, further supporting this mechanism [178]
Similarly, activating the Nrf2/HO-1 axis to enhance cellular antioxidant gene expression can hamper ferroptosis, although the potentially excessive iron release from high HO-1 expression must be considered (128)

An additionally important finding from the study of osthole effects in HER2-overexpressing breast cancer cells is that osthole could enhance paclitaxel-induced cytotoxicity in these cells
