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This inhibition preserves nicotinamide availability for the NAD+ salvage pathway, the primary route for NAD+ regeneration in mammalian cells

In the UK, vitamin B12 deficiency is relatively common, particularly among older adults, vegans, vegetarians, and individuals with certain gastrointestinal conditions that impair absorption, such as pernicious anaemia or Crohn's disease

In addition, this product has not been approved by the FDA for human use

This mitochondrial support may also contribute to healthy aging, as mitochondrial dysfunction is a hallmark of cellular aging

While AHK-Cu specific skin studies are limited, the shared mechanisms suggest similar benefits