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Description
Proteomic analysis of cells following treatment with loperamide and pimozide revealed that these drugs can induce endoplasmic reticulum stress, leading to increased ROS levels and promoting cell death (Meyer et al., 2021)
Redox Biol 1:4415
(95% CI: 0.48 to 1.03)
Therefore, lactate and lactylation-related subtype transformation of astrocytes and microglia may play a crucial role in the onset and progression of neuroinflammation
Metabolism: clinical and experimental
