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The estimated 5-year OS rate was 34% (95% CI, 30%38%), and the investigator-assessed PFS rate was 19% (95% CI, 15%22%)

53 However, it is estimated that a single remnant particle may carry up to 40 times more cholesterol than each LDL particle , amplifying its ability to promote foam cell formation, an early hallmark of atherosclerosis

[PubMed: 17709641] 176

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