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8 9 The consequences of mild or subclinical vitamin B 12 deficiency are less clear but it has been shown to be associated with decreased cognitive performance in both the elderly and children

In the clinical trial, participants who started at higher initial doses experienced significantly more gastrointestinal side effects than those who began at 2 mg

Side effects appear suddenly, cause discomfort, and don't relate to your treatment target

In addition, HPA-D impacts DHEA, estrogen, thyroid hormone, insulin, leptin, and other hormones that play a role in metabolism, eating behaviors 18 , and weight

Clinical studies suggest noticeable results after 812 weeks of consistent supplementation