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High expression of PRMT7 promotes the methylation of RAP1A regulatory element histones and regulates monocyte adhesion and migration

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Intraluminal injection of short chain fatty acids diminishes intestinal mucosa injury in experimental ischemia-reperfusion

Free amino acids in milks of human subjects, other primates and non-primates

Natural compounds like midazolam, vitamin B12, metformin, Cangrelor, and hesperidin have also shown anti-inflammatory effects in preclinical MIRI models, often by modulating macrophage polarization or inhibiting inflammatory pathways like NF-B (Xu et al., 2024)