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This multifactorial assault on glutathione homeostasis creates a compelling rationale for exogenous support, particularly through delivery methods that ensure reliable tissue concentrations
In other organisms where DHAR expression was studied, the genes were shown to be expressed in most tissues/organs
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The M1/M2 classification based on cytokine-induced polarization in vitro is a simplified model that does not reflect the macrophage heterogeneity in vivo
The Kyoto Encyclopedia of Genes and Genomes database ( was used to conduct a graph theoretical analysis 22,23
