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The high-potential redox chain, discussed in section The respiratory chain, is made up of one heme on cytochrome c 1 and the Fe-S cluster engaged by UQCRFS1

Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide

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Glutathione has a significant role in detoxifying dietary ethanol (alcoholic beverages), and anyone who drinks regularly will deplete their glutathione levels (6)
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