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For example, a patient with intestinal lymphangiectasia presented with gelatinous transformation of the bone marrow, which was resolved by treatment with a triglyceride-rich diet (326)

Nonetheless, whether the specific mechanism of this is related to the transdifferentiation of VSMCs to a bone-like phenotype, loss in SMC lineage markers, enhanced pro-calcific microRNAs, increased intracellular calcium level, apoptosis, or aberrant DNA damage response (DDR) requires further investigation

Caldeira-Brant AL, Martinelli LM, Marques MM, Reis AB, Martello R, Almeida FRCL, Chiarini-Garcia H (2020) A subpopulation of human Adark spermatogonia behaves as the reserve stem cell

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