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Ralph Carmel, one of the leading researchers on vitamin B12, published a study in 1988 with several subjects analyzed, suggesting a relationship between higher amounts of accumulated analogues and a greater risk of neurological symptoms, which could explain why some patients did not experience neurological symptoms (at least at the time) but did experience anemia

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The formation of persisters has been experimentally documented for major bacterial pathogens including Staphylococcus aureus ( Mycobacterium tuberculosis ( Escherichia coli ( Salmonella enterica ( Pseudomonas spp ( Listeria monocytogenes ( Legionella pneumophila (Personnic et al., 2019) , Burkholderia pseudomallei (Ross et al., 2019), and Yersinia pseudo-tuberculosis (Raneses et al., 2020)

Jain M, Ghanashyam C, Bhattacharjee A