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Trial registration This trial has been registered with ClinicalTrials.gov, number NCT 01476007, and under EUDRACT number 2010-024129-20

doi: 10.3390/genes10040260

662 Rational (targeted) engineering of transcription factors has been explored as a means to improve sensibility, metal specificity and/or expand the repertoire of analytes to be detected

The NRP-1-mediated SARSCoV2 entry into bone marrowderived macrophages (BMM) could impede osteoclast differentiation and affect calcium/phosphorus metabolism in COVID19 patients 328

Cultures (100 l per well) were aliquoted into Falcon 96-well white plates and mixed 1:1 with BacTiter-Glo reagent (Promega), then incubated in the dark on a rocker at room temperature for 520 min