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Description
Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents
IRS recruitment activates phosphoinositide 3-kinase (PI3K), which phosphorylates PIP2 to PIP3, recruiting Akt/PKB to the membrane for activation by PDK1 this PI3K/Akt arm drives protein synthesis via mTORC1, glucose uptake via GLUT4 translocation, and cell survival via BAD phosphorylation
Singh S, Tripathi DK, Singh S, Sharma S, Dubey NK, Chauhan DK
Luongo C, Ambrosio R, Salzano S, Dlugosz AA, Missero C, Dentice M
doi:10.1007/s10548-017-0547-1 89
