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[DOI] [PubMed] [Google Scholar] 59.Underwood LE, Backeljauw P

Intracellular ROS homeostasis is characterized by the ability of cells to adapt to changing conditions such as hypoxia, hyperoxia, and oxidative stress [4,5,6], while disruptions in this equilibrium can have significant implications for cell fate [7], disease progression [8], and therapeutic responses [9]

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While insufficient inositol metabolism may lower TSH signal transduction effectiveness [7], selenium shortage has been associated with decreased selenoprotein activity, increased oxidative stress, and an increased risk of autoimmune thyroiditis [2,18,36,47]