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doi: 10.1080/02640414.2016.1261176

From preclinical evidence to human studies: what makes a drug candidate ready for a First-in-Human trial

Symptoms of Vitamin B12 deficiency may include fatigue, weakness, pale skin, shortness of breath, tingling or numbness in hands and feet, and difficulty maintaining balance

deficit in the MS model system

Huberman does not include the supplement in his sleep toolkit blog on his website, but he has spoken about taking 900mg every three days to bolster his sleep stack during an episode of his podcast on the subject of OCD
