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Famularo G, Tzantzoglou S, Santini G, Trinchieri V, Moretti S, Koverech A, De Simone C

Poski R, Szymaski K, Bednarczuk T

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Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66