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L-carnitine may participate in the transport of fatty acids to the mitochondria, the energy-producing units of cells, making it particularly popular during the peri-workout period

The possible mechanisms that account for the beneficial response seen with L-carnitine in AMI are probably multifactorial and include, in part, an improvement in myocardial mitochondrial energy metabolism in the heart due to its ability to enhance the transport of long-chain fatty acids from the cytosol to the mitochondrial matrix where -oxidation occurs, removing toxic fatty acid intermediates, lessening ischemia secondary to elevated long-chain fatty acid concentrations, and replenishing the depleted carnitine concentrations seen in ischemic, infarct, and failing myocardium

In the murine model of lipopolysaccharide (LPS)induced ALI, severely impaired FAO in alveolar EpiCs participated in the inflammatory response and lung injury, which might be attributed to the decreased expression of key mediators involved in FAO, such as CPT1A, and could partly be counteracted by treatment with a PPAR agonist, fenofibrate ( CPT1A aggravated EC apoptosis and lung injury, while treatment with L-carnitine attenuated the pathological changes (Yao et al., 2019)

[DOI] [PubMed] [Google Scholar] 18.Rebouche C.J

Benefits: This advanced liquid L-Carnitine formula is designed to support metabolic thermogenesis, fat utilization, and cellular energy with a multi-pathway approach