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Upon re-exposure to the viral vector or pathogen, evolved memory B cells may differentiate into antibody-secreting plasma cells, undergo further evolution and acquire new mutations, and/or be induced to expand into new memory B cell clone [14,65], contributing to the formation of immune memory

Group constants are special micro constants when the rest of the groups in the molecule are far enough apart, and their protonation does not affect the basicity of the group [80]

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In this context, Yu et al