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Leuco-methylthioninium bis (hydromethanesulfonate) is one such compound that has been reported to prevent tau aggregation and has subsequently been tested in cell lines and a transgenic mouse model of PD with encouraging results (Schwab et al

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doi: 10.3390/pharmaceutics12111091 [DOI] [PMC free article] [PubMed] [Google Scholar] 96.Iba T, Levy JH, Hirota T, et al

Ji W, Zhu Y, Li Y, Yang L, Zhao X, Cai H, et al

10.1164/rccm.200703-500OC 80
