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Hear Res 446, 109004.Google Scholar Kim, EC, Toyono, T, Berlinicke, CA et al

For example, a mitoprotection bundle for high-risk surgery might include: a) a sulforaphane-based supplement a day before surgery (to activate Nrf2 antioxidant responses), b) remote ischemic preconditioning during anesthesia induction (209), c) low-dose IL-1ra (anakinra) at start of reperfusion, d) postoperative Dexmedetomidine infusion, and e) high-protein nutrition with omega-3 fatty acids to support recovery

Sublingual B12 contains cyanocobalamin or methylcobalamin and dissolves under the tongue within minutes

doi: 10.3389/fphar.2025.1648395 Received 17 June 2025 Accepted 08 September 2025 Published 03 October 2025 Volume 16 - 2025 Edited by Nunziatina De Tommasi, University of Salerno, Italy Reviewed by Sohail Mumtaz, Gachon University, Republic of Korea Lei Hu, Lushan Botanical Garden (CAS), China Updates Copyright 2025 Dubey, Chandragiri, Geevarghese, Kapoor, Gulati, Rani, Singh, Chavda, Gundamaraju, Bansal, Gautam, Goyal, Okoh, Shen and Singla