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The next day, after rewarming, the secondary antibody (1:200 dilution) was incubated in the dark for 1 h, stained with Hoechst-33258 (DAPI) at 1 g/mL, and the anti-quenching tablet was blocked

On the other hand, pyridoxine is the coenzyme of dopa decarboxylase, converting L-DOPA to dopamine 49 , which raises a concern that pyridoxine supplementation may result in peripheral metabolism of L-DOPA and a lack of bioavailability in the brain 58

Glutathione peroxidase 4 is associated with neuromelanin in substantia nigra and dystrophic axons in putamen of parkinsons brain

Vitamin C (as ascorbic acid)

A recent study also showed its connection to ATP synthase, where DJ-1 is required for the normal stoichiometry of ATP synthase and to facilitate positioning of the subunit of ATP synthase to fully close the mitochondrial inner membrane leak (Girotto et al., 2014)