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In many cases yes

[DOI] [PMC free article] [PubMed] [Google Scholar] 132.Logroscino G., Marder K., Cote L., Tang M.X., Shea S., Mayeux R

217,218,219 Deficiency of Cu could increase the level of total cholesterol, a key factor to increase atherosclerosis risk

During this process, the heme responsive gene-1 (Hrg1) is specifically recruited to the phagolysosomal membrane, where it strongly co-localizes with the lysosomal marker Lamp1 (91, 92)

In in vitro studies, however, GPx-1 inactivation by peroxynitrite is prevented by GSH (280, 327), in the presence of which GPx-1 can act as a peroxynitrite reductase
