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Even though choline is produced endogenously in the liver, it is still considered an essential nutrient because the quantities produced is not sufficient to meet the body's metabolic needs

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Many people, especially older adults, vegetarians, or those with certain health conditions, may not get enough of it

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WADA specifies in its S0 clause that any pharmacological substance without regulatory approval for human use is banned at all times in sport (World Anti-Doping Agency)