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Gong et al., 2020), YY1 (Wu et al., 2018), c-MYC (Yin et al., 2017), p65 (Zhang et al., 2020), TAp73 (Du et al., 2013), Nrf2 (Liu et al., 2015

Apply gently with a pad of cotton wool to the affected parts as required

The application of these models in toxico-metabolomic research can help identify potential drug toxicity issues early in drug development process, allowing for timely intervention (Figure 7)

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Therefore, inhibition of TXNIP should increase Trx1 activity