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Particularly in the context of PD, the concern for a limited capacity for long-distance axonal growth in the adult brain, has prompted the investigation of delivering growth-promoting cues in the striatum or the nigrostriatal bundle to guide axonal projections from homotopic transplants placed in the SNpc toward the striatum and reconstruct the lost midbrain DA pathways

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Validated questionnaires were used to assess pain, disability, and quality of life both at baseline and during a 2-month follow-up