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A primary challenge stems from the limitations of experimental models, which typically used pristine MPs with uniform properties, while real-world MPs are highly heterogeneous in size, shape, polymer composition, and surface chemistry, and are often altered by environmental exposure and the formation of eco-coronas [78]

These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)

I., Turk J Haematol 2016, 33, 15

A., Hayati, M

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