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In addition, there is evidence for increased expression of the Nox subunit Nox2 and Nox4 in atherosclerotic arteries, which may contribute to ATII-stimulated oxidative stress during hypertension and human atherosclerotic disease

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This multi-pathway anti-inflammatory approach may be more effective than either peptide alone at breaking the inflammation-degeneration cycle that characterizes chronic disc injuries

Mol Ther Nucleic Acids 20:882894