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Long-term safety endpoints had the primarily purpose of excluding the presence of infections due the possible non-sterility of the cell product (a risk minimized by the extensive in vitro examinations), tumor formation (risk minimized by the in vivo evidence obtained by infusion of supra maximal doses of cells in immunosuppressed mice) as well as changes in neurological status that would not be expected based on the disease course

J Neurosci 33:1150611514 Narayanan RT, Udvary D, Oberlaender M (2017) Cell type-specific structural organization of the six layers in rat barrel cortex

After a saline bath was applied to the colon segment that had been deprived of its blood supply, arcade vessels gradually disappeared from the proximal to the distal arcades

302,303,304 MIF has at least two catalytic activities: tautomerase and oxidoreductase activities

doi: 10.1016/j.psyneuen.2008.12.001 24 MoranLJKoHMissoMMarshKNoakesMTalbotMet al