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22 Similarly, in mouse gastric cancer tissue, lactylation of YAP at lysine 90 and TEAD at lysine 108 mediated by AARS1 activates the YAP-TEAD complex, promoting Hippo pathway gene expression and gastric cancer cell proliferation

CKD patients experience iron and lipid deposition, and the induction of ferroptosis in the kidney has been shown to cause renal fibrosis and disease progression [13,14]

Zheng J, Liu G, Tozkoparan B, Wen D

Bahadur S, Pardhi DM, Rautio J, Rosenholm JM, Pathak K

An interaction between metabolic pathways of homocysteine and gut microbiota has been reported, and specific microbial signatures have been found in individuals experiencing hyperhomocysteinemia