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PCOM on ultrasonography is considered a core feature of PCOS, which is relevant as a diagnostic criterion for PCOS, however, there remains a lack of clarity regarding the best practices and specific ultrasonographic markers to define PCOM [89]

For cretinism in iodine-deficient areas, Se supplementation should not be promoted prior to iodine supplementation or when there is no plan for iodine supplementation, as stated by the American Thyroid Association, The differential intakes of iodine, Se, or both in different regions must be considered before any action for Se supplementation is taken (69)

69 Inflammatory cells and mediators play a critical role in MODS development

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