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This therapeutic potential has already been demonstrated in many compounds

For example, the patients of chronic fatigue syndrome (CFS) have shown significant variations in the expression of genes encoding miRNAs that regulate cytotoxicity, cytokine secretion, and apoptosis, closely related to the high expression of immunoinflammatory genes encoding tumor necrosis factor- (TNF-), interleukin-6 (IL-6), and COX-2 in adolescent patients of CFS (Brenu et al., 2014

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Conclusion Many migraine triggers are related to brain energy metabolism disorders