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Disturbances in calciumphosphate metabolism, acidbase balance, and vitamin D synthesis are common in chronic kidney disease and have been linked to altered synaptic function, excitotoxicity, and reduced dopaminergic neuronal resilience [33]

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We have previously shown that 1 h treatment with elamipretide improves muscle function, increases sensitivity to ADP, and decreases ADP concentration in vivo [7, 14]

Nat Biotechnol 20(11):11401145 Diao Y, Xu H, Li G, Yu A, Yu X, Hu W et al (2014) Cloning a glutathione peroxidase gene from Nelumbo nucifera and enhanced salt tolerance by overexpressing in rice