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Decrease dose consideration: Persistent side effects including headaches, fatigue, or injection site reactions, excessive response (extremely rapid weight loss suggesting dose may be higher than needed), cost concerns when lower doses might achieve similar results
[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Singh P., Mishra G., Molla M., Shumet Yimer Y., Sisay W., Andargie Y., et al
In breast cancer (MCF-7) cells, silibinin triggers nuclear translocation of apoptosis-inducing factor (AIF), mediated by the inhibition of the ER pathway and enhanced autophagy [911]
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