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doi: 10.1080/19338244.2018.1492894 273 Tayri-WilkT.SlavinM.ZamelJ.BlassA.CohenS.MotzikA.et al

The stability of xCT is regulated by the MUC1-C (Mucin 1 C-terminal subunit)/CD44v (CD44 variant) complex, which directly interacts with xCT to promote its stability and control GSH levels[122]

Ingredients: Water, Centella Asiatica Extract (29.2%), Butylene Glycol, Propanediol, Niacinamide (20,000ppm), Glycerin, Diethoxyethyl Succinate, Panthenol, Sodium Hyaluronate, Allantoin, Glutathione (1,000ppm), Sodium Polyacryloyldimethyl Taurate, Glyceryl Acrylate/Acrylic Acid Copolymer, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Solanum Melongena (Eggplant) Fruit Extract, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hydrolyzed Collagen, Squalane, Beta-Glucan, Dipropylene Glycol, Hippophae Rhamnoides Fruit Extract, Adenosine, Madecassic Acid, Asiaticoside, Asiatic Acid, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Glyceryl Stearate, Cholesterol, Styrene/Acrylates Copolymer, Cellulose Gum, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Citric Acid, Disodium EDTA, Hydroxyacetophenone, 1,2-Hexanediol, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Sodium Citrate

However, they can have advantages for expressing complex proteins, such as those with post-translational modifications

Therefore, it is impossible to determine if IN GHK-Cu actually restored the aged hippocampus to a youthful transcriptomic state, or if it pushed the tissue into a novel, alternative compensatory state that simply happens to function better