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Mechanistically, regardless of ART treatment status, the dysregulation of monocyte subsets and proinflammatory programmes is partially driven by age- and HIV-associated impairments in haematopoietic stem cell differentiation [49, 50]

Published online 2014:129-

The presence of reducing agent, -mercaptoethanol in the Western blotting analysis prevented the appearance of high molecular bands, confirming that the protein oligomerization was induced by disulfide bonds