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However, concentrations exceeding 10 6 M inhibited the growth rate

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NNMT and NAD Metabolism By methylating nicotinamide, NNMT consumes NAM that would otherwise feed into the salvage pathways for NAD synthesis , thereby reducing intracellular NAD levels

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Knezevic T., Vranes H., Drmic D., Staroveski M., et al

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