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Description
But the reason she was able to do this is that she had a
Transl Neurodegener 4(1):18 Caputi V, Giron MC (2018) Microbiome-gut-brain axis and toll-like receptors in Parkinsons disease
In addition to mitochondria, the other important sources of superoxide radicals are xanthine oxidase (XO) and activated NADPH oxidase
These include lipid peroxidation products, e.g., F2-isoprostanes and malondialdehyde, DNA breakdown products (e.g., 8-OH-dG), protein adducts (e.g., carbonylated proteins), or antioxidant status
In the ischemia phase of I/R, induction of ALOX15 triggers oxidization of PUFA-phospholipids, especially PUFA-phosphatidyl ethanolamines (PEs) leading to cardiomyocyte ferroptosis [26, 27]
